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fenfluramine
Psychiatrische complicaties bij de behandeling van overgewicht met fenfluramine Nederlands Tijdschrift voor Geneeskunde.
De symptomen vinden vermoedelijk hun oorsprong in de sterke invloed die fenfluramine uitoefent op serotonerge neuronen. Er wordt geadviseerd fenfluraminetoediening met lage doses te beginnen en tenslotte via lage doses te beëindigen, en de stof niet voor te schrijven aan patiënten die reeds eerder stemmingsstoornissen hadden.
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Fenfluramine an overview ScienceDirect Topics. ScienceDirect. Elsevier. RELX Group.
The use of fenfluramine got a significant boost with the publication of a series of papers in 1992 7 that demonstrated the magnitude and sustainability of weight loss that could be seen when fenfluramine was combined with phentermine the combination that was known popularly as phen-fen, and in 1996, the FDA approved the d enantiomer of fenfluramine for the long-term treatment of obesity.
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Pondimin Fenfluramine Removed from US Market: Side Effects, Interactions, Warning, Dosage Uses.
Further depression of mood may become evident while the patient is on fenfluramine or following withdrawal of fenfluramine. Symptoms of depression occurring immediately following abrupt withdrawal can be readily controlled by reinstituting Fenfluramine HCl, followed by a gradual tapering off of the daily dose.
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Old Drug for New Indication? Fenfluramine and Dravet Syndrome.
In new five-year follow-up data from a long-term study presented May 28 at the 11th European Paediatric Neurology Society Congress 2015, in Vienna, Austria, low-dose 10 mg to 20 mg per day as oral liquid, added to current anti-epilepsy medication fenfluramine was effective and well tolerated.
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Fenfluramine.
At that time however, there were no cause for alarm and fenfluramine stayed on the shelves as the moderately prosperous weight-loss medication. By 1994 nonetheless, 41 cases of pulmonary hypertension had been discovered, however just four had been documented as getting the result of the intake of fenfluramine.
Verboden geneesmiddel voor behandeling dravetsyndroom UZ Leuven.
Dankzij de aanhoudende inspanningen van de onderzoekers, die wel goede resultaten zagen bij het gebruik van fenfluramine, kreeg men via een koninklijk besluit de toelating om onder strikte supervisie en enkel in Pulderbos de medicatie verder te geven aan kinderen met het dravetsyndroom.
Fenfluramine Wikipedia.
The combination of fenfluramine with phentermine, a norepinephrinedopamine releasing agent acting primarily on norepinephrine, results in a well-balanced serotoninnorepinephrine releasing agent with weaker effects of dopamine release. Fenfluramine, phentermine, and monoamine release EC 50, nM Drug NE DA 5-HT Type Ref.
fenfluramine C12H16F3N PubChem.
National Library of Medicine NCBI National Center for Biotechnology Information. OPEN CHEMISTRY DATABASE. This application requires Javascript. Please turn on Javascript in order to use this application. Data Citation Guidelines. National Center for Biotechnology Information, U.S. National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894, USA.
Fenfluramine DrugBank.
Caroxazone may increase the serotonergic activities of Fenfluramine. The risk or severity of adverse effects can be increased when Chlorproethazine is combined with Fenfluramine. The risk or severity of adverse effects can be increased when Chlorpromazine is combined with Fenfluramine.
De geschiedenis van dexfenfluramine Geneesmiddelenbulletin.
1974: De plaats van fenfluramine bij de behandeling van vetzucht is die van een gebrekkig adjuvans en Van de met fenfluramine behandelde patiënten vertoont ruim 80% bijwerkingen Gebu 1974; 8: 1-4. 1981: Eerste rapportage over optreden van pulmonale hypertensie bij gebruik van fenfluramine.

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